Fibromyalgia: heterogeneity in personality and psychopathology and its implications

Abstract

The fibromyalgia syndrome (FM) is a chronic widespread pain con dition whose etiology remains unknown and no treatment hassatisfactory levels of success. A meta-analysis has identified a distinct Minnesota Multiphasic Personality Inventory-2 (MMPI-2) clinical profile between FM female patients and healthy controls, and differences between FM and other chronic pain condition with clear etiology have also been found. However, heterogeneity in this population has been suggested in several studies. We aim to assess clinical aspects in FM patients, based on personality psychopathol ogy characteristics, in order to explore heterogeneity and the exis tence of core common aspects. In this cross-sectional study, a relatively homogeneous sample of 56 female FM patients (Mage = 45.95, SDage = 9.39) was assessed through MMPI-2. A K-Means cluster analysis identified two clusters, one (n = 24) with clinically significant levels in Negative Emotionality and Introversion scales. Subsequent MANOVAs identified important features of this cluster on several MMPI-2 dimensions. Moreover, several dimensions are clinically elevated in both clusters. In conclusion, the combination of psychopathological negative emotionality, interpersonal isola tion, and low hedonic capacity, in a group of patients, has implica tions for the daily living and treatment of FM patients, and several core aspects of FM need to be addressed.